Which oral lesion is likely to be treated with corticosteroids?

The major aphthous ulcer, or major canker sore, is often treated with corticosteroids due to its significantly larger size and more severe pain compared to minor aphthous ulcers. These lesions can be quite debilitating and may take longer to heal. Corticosteroids can help reduce the inflammation and pain associated with these ulcers, promoting healing and improving patient comfort.

In contrast, while minor aphthous ulcers are also treated effectively but may often resolve on their own and with topical therapies rather than systemic corticosteroids. Cold sores, caused by the herpes simplex virus, are typically managed with antiviral medications rather than corticosteroids. Oral fibromas are benign growths that usually do not require inflammatory treatment but instead may be surgically excised if necessary. Thus, corticosteroids are a suitable choice for managing the inflammation and discomfort of major aphthous ulcers specifically.